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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFCAB4B
All Species:
11.82
Human Site:
S246
Identified Species:
28.89
UniProt:
Q9BSW2
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BSW2
NP_116069.1
395
45592
S246
E
M
E
Q
Q
I
K
S
E
K
E
Q
F
L
L
Chimpanzee
Pan troglodytes
XP_001156341
349
40105
C220
E
E
K
N
E
L
E
C
A
L
K
R
K
I
A
Rhesus Macaque
Macaca mulatta
XP_001099191
395
45802
S246
E
M
E
Q
Q
I
K
S
E
K
E
Q
F
L
L
Dog
Lupus familis
XP_543866
546
63029
H237
E
M
E
Q
Q
I
K
H
E
K
E
Q
F
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3UP38
310
35821
K182
Q
L
W
L
Q
L
R
K
D
E
P
H
L
L
S
Rat
Rattus norvegicus
XP_575675
803
91156
S317
E
M
E
Q
Q
I
K
S
E
R
E
Q
F
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P0CB05
711
81982
Q296
K
L
H
Q
E
Q
L
Q
K
E
L
A
R
V
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922837
334
39046
T205
Q
E
K
K
E
M
E
T
A
L
K
R
K
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785593
232
26649
R105
E
A
L
L
S
V
S
R
R
R
R
R
Q
Q
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
R756
D
L
Q
N
R
C
E
R
V
V
E
L
E
I
S
Conservation
Percent
Protein Identity:
100
82.7
96.4
59.5
N.A.
57.7
38.3
N.A.
N.A.
21.2
N.A.
45.3
N.A.
N.A.
N.A.
N.A.
22.5
Protein Similarity:
100
84.3
97.9
63.9
N.A.
66
44.4
N.A.
N.A.
34.3
N.A.
61.7
N.A.
N.A.
N.A.
N.A.
39.2
P-Site Identity:
100
6.6
100
93.3
N.A.
13.3
93.3
N.A.
N.A.
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
53.3
100
93.3
N.A.
53.3
100
N.A.
N.A.
46.6
N.A.
60
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
30
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
20
0
0
10
0
0
20
% A
% Cys:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
60
20
40
0
30
0
30
0
40
20
50
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
40
0
0
0
0
0
0
0
20
0
% I
% Lys:
10
0
20
10
0
0
40
10
10
30
20
0
20
0
0
% K
% Leu:
0
30
10
20
0
20
10
0
0
20
10
10
10
50
40
% L
% Met:
0
40
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% P
% Gln:
20
0
10
50
50
10
0
10
0
0
0
40
10
10
0
% Q
% Arg:
0
0
0
0
10
0
10
20
10
20
10
30
10
0
0
% R
% Ser:
0
0
0
0
10
0
10
30
0
0
0
0
0
10
20
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
0
10
10
0
0
0
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _